X-Nico

unusual facts about Flavanone 4-reductase


Flavan-4-ol

Flavanone 4-reductase is an enzyme that uses (2S)-flavan-4-ol and NADP+ to produce (2S)-flavanone, NADPH, and H+.


Aldose reductase inhibitor

Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes.

Aromadendrin

The enzyme dihydrokaempferol 4-reductase uses cis-3,4-leucopelargonidin and Arsenate-reducing bacteria

It appears that arsenate reduction by the Desulfovibrio strain Ben-RA is catalyzed by an arsenate reductase that is encoded by a chromosomally-borne gene shown to be homologous to the arsC gene of the Escherichia coli plasmid, R773 ars system.

Bisphosphonate

Statins are another class of drugs that inhibit the HMG-CoA reductase pathway.

Denitrifying bacteria

Denitrifying bacteria form a necessary part of the process known as denitrification as part of the nitrogen cycle, their primary purpose being to metabolise nitrogenous compounds, with the assistance of the nitrate reductase enzyme, to turn oxides back to nitrogen gas or nitrous oxides for energy generation.

Dihydrofolic acid

Since tetrahydrofolate is needed to make both purines and pyrimidines, which are building blocks of DNA and RNA, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis.

F430

Cofactor F430, F430, the prosthetic group of the enzyme methyl coenzyme M reductase

Flutamide

LH stimulates the testes to produce testosterone, which is metabolized to DHT by the enzyme 5α-reductase.

FNRS

FnrS RNA, fumurate and nitrate reductase regulator small RNA

Glycerate dehydrogenase

Glyoxylate Reductase/Hydroxypyruvate Reductase (GRHPR) is the glycerate dehydrogenase found, predominantly in the liver, of humans encoded by the gene GRHPR.

Nitrate reductase

A transmembrane nitrate reductase that can function as a proton pump (similar to the case of anaerobic respiration) has been discovered in a diatom Thalassiosira weissflogii.

Robert B Mellor

However Mellor was also interested in applied science and invented and a patented system to power immobilized oxido-reductase enzymes and artificial co-factors using electrical power out of a domestic socket.

Sitosterolemia

Patients have markedly reduced whole-body cholesterol biosynthesis associated with suppressed hepatic, ileal, and mononuclear leukocyte hydroxymethylglutaryl-coenzyme A reductase (HMG-CoA reductase), the rate-controlling enzyme in the cholesterol biosynthetic pathway.


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