Both the Strickland and the Ok Tedi Rivers have been the source of environmental controversy due to tailings waste from the Porgera Mine and the Ok Tedi Mine, respectively.
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The estuary of the Fly River is 56 km wide at its entrance, but only 11 km wide abreast Kiwai Island, which may be considered as being the river mouth.
Luigi Maria D'Albertis (November 21, 1841 – September 2, 1901) was a flamboyant Italian naturalist and explorer who, in 1876, became the first person to chart the Fly River in Papua New Guinea.
Zappa confluentus, the New Guinea slender mudskipper, endemic to New Guinea where it is only known from the lower parts of the Fly, Ramu and Bintuni Rivers.
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It is also 55 km southeast of the mouth of the Fly River of Papua New Guinea, at the southeastern tip of Kiwai Island.