One sad note was the loss during a shipwreck of a large assembly of Italian works, including a Pietá by Sebastiano del Piombo and a series of paintings from the City council of Lucca.
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He met Titian and arranged for the emperor's portrait by the famed Venetian artist.
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He is known to have given an Aztec manuscript bound in tiger skin to the historian Paolo Giovio in Naples.
He also worked on a number of manor houses including the Palace de Dueñas in Medina del Campo, and the Francisco de los Cobos Palace in Valladolid (the Valladolid Royal Palace).
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