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Ambrose and Gregory the Great, who are known for their contributions to the formulation of Gregorian chant, are credited with 'antiphonaries', collections of works suitable for antiphon, which are still used in the Roman Catholic Church today.
It consists of five manuscript folios, contains quotes from the Vulgate and Vetus Latina Bible; patristic commentary by Augustine, Jerome, Cyprian, Origen, Ambrosiaster and Gregory the Great; extracts from Canon law, ecclesiastical history and synodal decrees from Nicea and Arles in their original, uncontaminated forms, in addition to a decretum that enjoined on the Irish that, if all else failed, they should take their problems to Rome.
In 419, Eulalius, competitor of Pope Boniface I, was made Bishop of Nepi; Bishop Paulus was sent as visitor to Naples by Gregory the Great; Bishop Stephanus, in 868, was one of the presidents and papal legates of the Council of Constantinople against Photius.
The first known Bishop of Squillace is Gaudentius (465); Zachæus accompanied Pope Vigilius to Constantinople (551); John, previously Bishop of Lissa, in Dalmatia, having been driven out by the barbarians, was transferred to Squillace by Gregory the Great.
Some writers declare that they know nothing of its origin and history; others, on the contrary, trace it back to the translation of the Holy House (1294); others, to Pope Sergius I (687); others, again, to Gregory the Great or to the 5th century; while others go as far back as the earliest ages of the Church, and even Apostolic times.
Manegold's book also contained an account of the life of Gregory VII, reflecting the Vita by John the Deacon of Gregory the Great; this shares details with chronicles of Berthold of Reichenau and Bernold of St Blasien, writing in the part of southern Germany in which Manegold had sheltered after having to leave Alsace.
His pastoral activities included service at the parishes of St. Gregory the Great in Sliema and Transfiguration in Iklin.