The Neonatal Fc receptor which in case of humans transfer the maternal antibody from mother through placenta to fetus, in this case is involved in transporting the IgG1 antibodies from mother animal's mammary gland into milk and then again from the ingested milk across the newborn intestine into the newborn animal's circulation.
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Hemolytic disease is a well-known condition in newborn foals, especially in Thoroughbreds and mules.
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In 1968, Ortho introduced RhoGAM Rho(D) immune globulin, the first medication developed to prevent Rh hemolytic disease of the newborn.
William Pollack (February 26, 1926 – November 3, 2013) was a British-born American immunologist who developed the Rho(D) immune globulin vaccine against Rh disease, a leading cause of erythroblastosis fetalis.