Two of the most notorious of these abuses were the experiments of Nazi physicians that became a focus of the post-World War II Doctors' Trial, and the Tuskegee Syphilis Study, a project conducted between 1932 and 1972 by the U.S. Public Health Service on black men in rural Alabama.
Prior to publication, the book and its authors were criticized for their non-standard research methodology, aspects of their core premise, and lack of institutional review.
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