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3 unusual facts about Matthew P. Denn


145th Delaware General Assembly

This date was January 6, 2009, which was two weeks before the beginning of the first administrative year of Democratic Governor Jack A. Markell from New Castle County and Democratic Lieutenant Governor Matthew P. Denn, also from New Castle County.

Matthew P. Denn

As Governor Ruth Ann Minner's legal counsel from 2001 through 2003, writing legislation including the Patient's Bill of Rights and the Emergency Health Powers Act.

A graduate with honors and student body president at the University of California, Berkeley, he received his law degree from Yale Law School in 1991.


Hox gene

In 1983, the homeobox was discovered independently by researchers in two labs: Ernst Hafen, Michael Levine, and William McGinnis (in Walter Gehring's lab at the University of Basel, Switzerland) and Matthew P. Scott and Amy Weiner (in Thomas Kaufman's lab at Indiana University in Bloomington).

Matthew P. Scott

Among his laboratory's many subsequent discoveries, he is recognized for the cloning of the patched gene family and demonstration that a human homolog PTCH1 is a key tumor suppressor gene for the Hedgehog signaling pathway as well as the causative gene for the nevoid basal cell carcinoma syndrome, or Gorlin syndrome.

Patched

The original mutations in the ptc gene were discovered in the fruit fly Drosophila melanogaster by 1995 Nobel Laureates Eric F. Wieschaus and Christiane Nusslein-Volhard and colleagues, and the gene was independently cloned in 1989 by Joan Hooper in the laboratory of Matthew P. Scott, and by Philip Ingham and colleagues.

Rocky Point Manor

The woodwork and mouldings in the home, attributed respectively to Matthew P. Lowery, the most famous Federal craftsman of the time, and John Rogers, the most famous foreign architect in Kentucky, are also a testament to the costliness of the house.


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