Although he recognized the necessity for the government taking measures with the object of regulating its attitude towards the Church, and declared himself prepared in his official capacity to carry out the May Laws, his confirmation was refused by the administration on 8 May 1875, a measure which resulted in an interpellation by Windt-Lorst in the Reichstag and the Prussian Diet.
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The wave of pogroms of 1881–1884 and anti-Semitic May Laws of 1882 introduced by Tsar Alexander III of Russia prompted mass emigration of Jews from the Russian Empire.
Due to the May Laws, he was imprisoned for at least two years, according to William James Sidis' biographer, Amy Wallace.
In the Russian Empire, waves of pogroms of 1881-1884 (some allegedly state-sponsored), as well as the and anti-Semitic May Laws of 1882 introduced by Tsar Alexander III of Russia, deeply affected Jewish communities.
After the pogroms following the May Laws, he helped found the Hovevei Zion in Warsaw, and convinced Baron Edmond James de Rothschild to financially support a settlement called Ekron (now Qiryat Ekron).
The May Laws introduced by Tsar Alexander III of Russia in 1882 banned Jews from rural areas and towns of fewer than ten thousand people.
In October 1873 the Mainz bishop and Centre Party founder Wilhelm Emmanuel Freiherr von Ketteler, having publicly condemned the May Laws on a pilgrimage to Kevelaer, was arrested and sentenced to two years in prison, resulting in fierce protests.