X-Nico

unusual facts about Necrosis


Debridement

Caption = Necrotic tissue from the left leg is being surgically debrided in a patient with necrotizing fasciitis.


Bowel resection

It may be performed due to cancer, necrosis, enteritis, diverticular disease, or a block in the intestine due to scar tissue.

Cauterization

Cantharidin: An extract of the blister beetle that causes epidermal necrosis and blistering; used to treat warts.

Dieter Matthaei

Matthaei D, Frahm J, Haase A, Schuster R, Bomsdorf H. Chemical-shift-selective magnetic-resonance imaging of avascular necrosis of the femoral head.

Etanercept

First, the developers isolated the DNA sequence that codes the human gene for soluble TNF receptor 2, which is a receptor that binds to tumor necrosis factor-alpha.

Hibernia

Another occurrence is in familial Hibernian fever or TRAPS (tumor necrosis factor receptor-associated periodic syndrome), a periodic fever first described in 1982 in a family of Irish and Scottish descent, but found in all ethnic groups.

Norrie disease

The diagnosis included a pseudotumor of the retina, hyperplasia of retinal, ciliary, and iris pigment epithelium, hypoplasia and necrosis of the inner layer of the retina, cataract, and Phthisis bulbi.

Paul Janssen

2008: Professor Marc Feldmann, FMedSci, FAA, FRS and Emeritus Professor Sir Ravinder Maini, FRCP, FMedSci, FRS of The Kennedy Institute of Rheumatology, Imperial College London, received the 2008 Dr. Paul Janssen Award for their role in the discovery of tumor necrosis factor-alpha, or TNF-alpha, as an effective therapeutic target for rheumatoid arthritis and other autoimmune diseases.

Radium jaw

The symptoms are necrosis of the mandible (lower jawbone) and the maxilla (upper jaw) as well as constant bleeding of the gums and (usually) after some time, severe distortion due to bone tumours and porosity of the lower jaw.

RANKL

This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor 6 (TRAF6), which indicated this protein may have a role in the regulation of cell apoptosis.

Sloughing

Eschar- piece(s) of necrotic tissue that are dead and cast off from the surface of the skin from wounds as part of the healing process.

White pox disease

White pox disease (also called acroporid serratiosis and "patchy necrosis"), first noted in 1996 on coral reefs near the Florida keys, is a coral disease affecting Elkhorn coral (Acropora palmata) throughout the Caribbean.


see also