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Rex Stout used Rowcliff, under whom he had at one time served and came to greatly dislike, as the model for Lieutenant George Rowcliff in the Nero Wolfe series of novels.
Other members of the principal cast of The Golden Spiders who would continue in the A&E series A Nero Wolfe Mystery include Bill Smitrovich (Inspector Cramer), Colin Fox (Fritz Brenner), Fulvio Cecere (Fred Durkin), R.D. Reid (Sergeant Purley Stebbins) and Trent McMullen (Orrie Cather).
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Saul Rubinek, who would take the role of Lon Cohen in the series, was cast as Saul Panzer in the pilot.