Thomas Stretch was among the leading citizens of Philadelphia and one of the founders of Pennsylvania Hospital.
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After Francis' death, Franklin became involved in promoting inoculation in Philadelphia: he published many studies on its value, working with several physicians, including the famed William Heberden at the Pennsylvania Hospital, which he helped found.
Pennsylvania Hospital, the first hospital in the British American colonies, and The Academy and College of Philadelphia, the predecessor to the private University of Pennsylvania, both opened.