DE 100 was first designated in the 1930s to run from DE 52 to the Pennsylvania border, where it originally connected to Pennsylvania Route 100 (PA 100).
The route continues north into South Coventry Township, meeting Pennsylvania Route 23 in the village of Bucktown.
•
One of those exits is in Douglass Township when PA 100 meets Pennsylvania Route 73 at a Diamond interchange.
Farther east, PA 401 heads into more wooded areas of homes as it crosses into West Vincent Township and reaches the PA 100 junction.
Here, the road turns northwest onto Creek Road (the old alignment of PA 100) prior to continuing northeast along Lenape Road into East Bradford Township.
PA 663 begins at an intersection with PA 100 in Pottstown, Montgomery County, heading east on four-lane undivided West King Street.
•
Its northern terminus is at PA 309 and PA 313 in Quakertown, where it continues eastward as PA 313, and its southern terminus is at PA 100 in Pottstown.
Pennsylvania | University of Pennsylvania | Billboard Hot 100 | Pennsylvania State University | Pennsylvania Railroad | Harrisburg, Pennsylvania | ''Billboard'' Hot 100 | Pennsylvania House of Representatives | Erie, Pennsylvania | 100 metres | Carlisle, Pennsylvania | Williamsport, Pennsylvania | Scranton, Pennsylvania | West Chester, Pennsylvania | Montgomery County, Pennsylvania | Lancaster, Pennsylvania | Bethlehem, Pennsylvania | U.S. Route 66 | Hershey, Pennsylvania | York, Pennsylvania | U.S. Route 1 | Pennsylvania Turnpike | Pennsylvania Academy of the Fine Arts | Wharton School of the University of Pennsylvania | University Park, Pennsylvania | Wilkes-Barre, Pennsylvania | Johnstown, Pennsylvania | Gettysburg, Pennsylvania | Reading, Pennsylvania | Luzerne County, Pennsylvania |
Its villages include Congo, Englesville (also in Berks County,) Gilbertsville, Niantic, and Sassamansville (also in New Hanover Township.) Its principal routes are Route 73 east-to-west and Route 100 north-to-south.