In the Pinky and the Brain episode "Brain's Song" (a pun on the film Brian's Song), he broadcasts a tearjerker sports movie to the entire world, using an electric football game as his field, and broadcasts the movie to the entire world to make them emotionally weak and allow him to take over the world.
Before the first/second part of Pinky and the Brain, Reggie gives this instruction and everyone gets in a weird position in order to watch "Pinky and the Brain".
In the cartoon episode You Said a Mouseful from Pinky and the Brain, both Pinky and Brain go through a collage of tongue-twisters that cover almost every category possible.
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He has written for television shows such as The PJs, George & Leo, Men Behaving Badly, Brother's Keeper, Gary & Mike, George of the Jungle, Pinky and the Brain, Duckman, Drawn Together, The Mullets, 3 South, and Tak and the Power of Juju.
A Primetime Emmy winner, Mills was best known for his work with Warner Bros. Animation, including Animaniacs, Tiny Toons Adventures, and Pinky and the Brain.
Animaniacs characters Pinky and the Brain paid homage to the show by having a puppet show called "The Meany Show" starring Meany and Treacle (both voiced by Maurice LaMarche) in the episode "Puppet Rulers" where Pinky and the Brain tried to use the show and a cryogenic chamber in order gain loyal followers in the future which didn't go as planned.