X-Nico

unusual facts about Polymerase chain reaction



Biosearch Technologies

When Kary Mullis received the Nobel Prize in 1993 and gave his Nobel Lecture concerning his invention of the polymerase chain reaction (PCR) method, he gratefully acknowledged Biosearch and Dr. Cook's role in providing him one of the first SAM I DNA synthesizers which was used in support of Kary Mullis' PCR research.

Cave of the Crystals

No DNA from ancient bacteria could be extracted from the solid inclusions and amplified by PCR.

Encephalitis

Diagnosis is often made with detection of antibodies in the cerebrospinal fluid against a specific viral agent (such as herpes simplex virus) or by polymerase chain reaction that amplifies the RNA or DNA of the virus responsible (such as varicella zoster virus).

Human Microbiome Project

The project also is financing deep sequencing of bacterial 16S rRNA sequences amplified by polymerase chain reaction from human subjects.

Preimplantation genetic diagnosis

Kary Mullis conceived PCR in 1985 as an in vitro simplified reproduction of the in vivo process of DNA replication.


see also