Class I RNR enzymes are constructed from large RNR1 and small RNR2 subunits which associate to form an active heterodimeric tetramer.
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Gallium inhibits RNR2 by substituting for Fe3+ in the active site.
5-alpha reductase | HMG-CoA reductase | Rubredoxin—NAD(P)+ reductase | Ribonucleoside-triphosphate reductase | GMP reductase | Flavanone 4-reductase | D-xylose reductase |