X-Nico

unusual facts about Serine


Transportin-3

TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, including Serine/arginine-rich splicing factor 1, which are essential precursor-mRNA splicing factors.


C14orf102

The protein contains five HAT (histone acetyltransferase) domains, a coiled coil domain, a domain of unknown function, a lysine-rich region, and a poly-lysine and serine region.

C4b-binding protein

C4BP accelerates decay of C3-convertase and is a cofactor for serine protease factor I which cleaves C4b and C3b.

CELA2A

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin.

Discovery and development of direct thrombin inhibitors

As the name indicates the cascade is a multi-step procedure where the main product thrombin is made by activating various proenzymes (mainly serine proteases) in each step of the cascade.

Discovery and development of triptans

This energetically favorable position of the agonist makes it possible for additional binding of the ligand to other Ser in the binding site, along with additional anchoring between Phe in the pocket of the binding site and the indole of the agonist.

GALNT1

GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.

Gustav Bartholin Hagen

Gustav Bartholin Hagen was born on 12 February 1873 in Copenhagen, the son of Sophus Hagen, a composer and music editor, and Serine Johanne Frederikke Klingsey.

Johan Jeremiassen

In 1870 Johan Jeremiassen married Serine, sister of later mayor Jørgen Christian and later Prime Minister Gunnar Knudsen.

Kallikrein 7

KLK7, a serine protease that in humans is encoded by the KLK7 gene

Phosphopeptide

Phosphorylation of serine and threonine residues is conserved during MHC class I and MHC class II antigen processing.

Polo kinase

Examples and other names in common use include Cdc5, Cdc5p, Plk, PLK, Plk1, Plo1, POLO kinase, polo serine-threonine kinase, polo-like kinase, polo-like kinase 1, serine/threonine-specific Drosophila kinase polo, and STK21.

STARD13

The protein consists of an N-terminal sterile alpha motif (SAM) domain, a serine-rich domain, a RhoGAP domain and at the C-terminus, a StAR-related lipid-transfer domain (START).

Theramine

Theramine is a specialized formula that consists of: Choline Bitartrate, L-arginine, L-histidine HCL, L-glutamine, L-serine, GABA, Griffonia Seed (95% 5HTP), Whey Protein Hydrolysate, Grape Seed Extract (85% Polyphenols), Cinnamon, and Cocoa Extract (6% Theobromine)

Transforming growth factor beta superfamily

These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and generate intracellular signals using a conserved family of proteins called SMADs.

Trichorrhexis invaginata

The Netherton syndrome Mendelian Inheritance in Man is inherited as an autosomal recessive disorder due to mutations of both copies of the SPINK5 gene (localized to band 5q31-32), which encodes the serine protease inhibitor LEKTI (lymphoepithelial Kazal-type-related inhibitor).

Trypsinogen

A further safeguard against inappropriate trypsin activation is the presence of inhibitors such as bovine pancreatic trypsin inhibitor (BPTI) and serine protease inhibitor Kazal-type 1 (SPINK1), which binds to any trypsin formed.


see also