The Swern oxidation, named after Daniel Swern, is a chemical reaction whereby a primary or secondary alcohol is oxidized to an aldehyde or ketone using oxalyl chloride, dimethyl sulfoxide (DMSO) and an organic base, such as triethylamine.
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; Swern, D. title = Structure of the dimethyl sulfoxide-oxalyl chloride reaction product.
Daniel Swern | Swern oxidation | Jones oxidation | In situ chemical oxidation | Beta oxidation |
Palladium on carbon hydrogenation removed the benzyl protecting group allowing the Swern oxidation of 2.10 to ketone 2.11