After being produced, the stability and distribution of the different transcripts is regulated (post-transcriptional regulation) by means of RNA binding protein (RBP) that control the various steps and rates of the transcripts: events such as alternative splicing, nuclear degradation (exosome), processing, nuclear export (three alternative pathways), sequestration in DCP2-bodies for storage or degradation, and ultimately translation.
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Poly(A)-binding protein (PABP) binds to a long poly(A) tail and mediates the interaction between EIF4E and EIF4G which encourages the initiation of translation.
General transcription factors These transcription factors position RNA polymerase at the start of a protein-coding sequence and then release the polymerase to transcribe the mRNA.
regulation | Allosteric regulation | Regulation | Regulation and licensure in engineering | Prudential Regulation Authority | International Centre for Financial Regulation | Compliance (regulation) | Regulation of gene expression | Regulation (European Union) | Public Worship Regulation Act 1874 | Prudential Regulation Authority (United Kingdom) | Olive oil regulation and adulteration | Florida Department of Environmental Regulation | Federal Regulation of Lobbying Act of 1946 | Coordinated Framework for Regulation of Biotechnology | Commission for Energy Regulation | Canadian securities regulation | Canadian Aviation Regulation Advisory Council | Bank regulation |
The heat shock protein, HSP60 is also known to be a target for post-transcriptional regulation by miR-1 and miR-206.