It then interchanges with I-80 Business, also signed as U.S. Route 50.
U.S. Route 66 | U.S. Route 1 | U.S. Route 6 | U.S. Route 101 | Route 66 | U.S. Route 30 | New Jersey Route 4 | European route E65 | U.S. Route 40 | California State Route 1 | U.S. Route 1 in Maine | Pennsylvania Route 309 | European route E18 | U.S. Route 23 | European route E4 | U.S. Route 9 in New York | U.S. Route 11 | Pennsylvania Route 82 | European route E70 | U.S. Route 90 | U.S. Route 75 | U.S. Route 61 | U.S. Route 60 | Pennsylvania Route 73 | New York State Route 32 | European route E55 | U.S. Route 80 | U.S. Route 71 | U.S. Route 51 | U.S. Route 22 |
On October 4, 2013, Mars was driving alone on U.S. Route 50 in Aldie, near her home in The Plains in northern Virginia, at about 2:30 pm when her 2004 Porsche SUV crossed the highway center line and struck a Chrysler minivan carrying six passengers.
The monument and tomb of U.S. President William Henry Harrison is located just off U.S. Route 50 in the township, and his former residence is located in nearby North Bend.
That is where U.S. Route 50, the "Loneliest Highway in America", crosses the range, connecting the nearby community of Ely with the Great Basin National Park and west-central Utah.
The Lincoln Memorial Bridge Pylons are a public artwork by French artist Raoul Josset, located on the Lincoln Memorial Bridge on U.S. Route 50 on the grounds of the George Rogers Clark National Historical Park.