The department is doing regular cardiac catheterization for congenital lesions and has started transcatheter treatment of suitable congenital disorders like ASD, PDA, pulmonary stenosis and mitral stenosis.
DLGAP2 has been shown to interact with DLG4, the canonical synapse marker protein, which in turn binds to N-methyld-aspartate (NMDA) receptors and Shaker-type K+ channels.
3,4-AHBAm is made via the aminoshikimate pathway from L-Aspartate-4-semialdehyde and Dihydroxyacetone phosphate via an enzyme catalyzed aldol condensation followed by ring formation.
The conversion of ATP, L-aspartate, and 5-aminoimidazole-4-carboxyribonucleotide (CAIR) to 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide, ADP, and phosphate by phosphoribosylaminoimidazolesuccinocarboxamide synthetase (SAICAR synthetase) represents the eighth step of de novo purine nucleotide biosynthesis.
The name RTX (repeats in toxin) refers to the glycine and aspartate-rich repeats located at the C-terminus of the toxin proteins, which facilitate export by a dedicated T1SS encoded within the rtx operon.