X-Nico

unusual facts about assay


Eva Nogales

Her lab uses electron microscopy, computational image analysis as well as functional biochemical assays to gain insights into function and regulation of the large biological assemblies.


ATP-binding cassette transporter

A typical example of an indirect vesicular transport assay is the detection of the inhibition of taurocholate transport by ABCB11 (BSEP).

Bioanalysis

The most frequently used techniques are: liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) for 'small' molecules and enzyme-linked immunosorbent assay (ELISA) for macromolecules

Birmingham Assay Office

The Birmingham Assay Office moved from the pub in 1815 to its own offices at Little Cannon Street and then moved to its current home on Newhall Street in the Jewellery Quarter in 1877, and is now the largest Assay Office in Europe, hallmarking 13 million articles in 2003.

BRT Laboratories

BRT’s tuberculosis (TB) testing is performed using the Interferon-gamma release assay T-SPOT.TB.

Chromatin immunoprecipitation

Matrix ChIP: This is a microplate-based ChIP assay with increased throughput and simplified the procedure.

Cytotoxicity

Cytotoxicity can also be monitored using the 3-(4, 5-Dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide (MTT) or MTS assay.

Ecarin clotting time

Ecarin, the primary reagent in this assay, is derived from the venom of the saw-scaled viper, Echis carinatus.

Elisa

ELISA or Enzyme-Linked Immunosorbent Assay, a biochemical technique

Ffn

Fetal fibronectin protein or its assay from vaginal secretion to assess risk of premature delivery

HoloVID

Many corporations (Kodak, Immunex, Boeing, Johnson and Johnson, Aerospace Corp., Silverline, and others) use customized versions of the Six Dimensional Non-Contact Reader w/ Integrated Holographic Optical Processing, for applications from SuperComputer Surface Mount pad assessment, to Genetic Biochemical Assay Analysis.

Mary Shaw Shorb

Mary Shaw Shorb (January 11, 1907 – August 18, 1990), a research scientist, was best known for the development of a bacteriological assay procedure for the chemical compound now known as Vitamin B12.

With the assay breakthrough, Folkers and his Merck team isolated crystals of the active ingredient – Vitamin B12 – from multiple sources within about three months.

Mir-129 microRNA precursor family

GALNT1, N-acetylgalactosaminyltransferase 1 – involved in TGF-β signalling, is another target of miR-129 that was identified by luciferase assay.

Oxygen radical absorbance capacity

The assay measures the oxidative degradation of the fluorescent molecule (either beta-phycoerythrin or fluorescein) after being mixed with free radical generators such as azo-initiator compounds.

Resazurin

It was introduced commercially initially under Alamar Blue trademark (Trek Diagnostic Systems, Inc), and now also available under other names such as AB assay, Vybrant (Molecular Probes) and UptiBlue (Interchim).

Rubicon Minerals

In September 1999 Rubicon announced encouraging assay results from a large sulphide discovery on the Palmer project near Haines, Alaska.

Sapio Sciences

This offering enables a single solution for managing clinical study data, treatment groups data, subject data, sample data and assay data from diverse assays such as Immunohistochemistry, Western Blot, PCR, etc.

Sheffield Assay Office

In 1773, Sheffield's silversmiths joined with those of Birmingham to petition Parliament for the establishment of Assay Offices in their respective cities.

Strictly standardized mean difference

In an HTS assay, one primary goal is to select compounds with a desired size of inhibition or activation effect.

can display both average fold change and SSMD for all test compounds in an assay and help to integrate both of them to select hits in HTS experiments

An important QC characteristic in an HTS assay is how much the positive controls, test compounds, and negative controls differ from one another in the assay.

Tapinoma sessile

They labeled sucrose with Immunoglobin G (IgG) proteins, and then identified them using an enzyme-linked immunosorbent assay (ELISA) to track the movement of food.

Toxocaridae

Direct identification of larvae in human disease is not feasible, so the diagnosis relies on history supported by serologic ELISA assay.

Tunel

TUNEL assay (Terminal deoxynucleotidyl transferase mediated dUTP Nick End Labeling assay), in genetics, a method for detecting DNA fragmentation

United States Assay Commission

The United States Assay Commission was an agency of the United States government from 1792 to 1980.

Virus quantification

ELISA is a more modern variation of a protein assay that utilizes a specific antibody linked to an enzyme to detect the presence of an unknown amount of antigen (i.e. virus) in a sample.

Wi, Inc.

Wi has worked on many point-of-care tests, including designing and prototyping a disposable card, hardware, and mixing on-card assay, and readying the Point-of-Care DNA-MRSA test for full PC control and lab use.

William Francis Hillebrand

After returning home to the United States in 1878, he opened an assay office in Leadville, Colorado, in 1879, and then started working as a chemist at the United States Geological Survey in 1880.

Xmap

xMAP (Multi-Analyte Profiling) technology is a multiplex assay format, patented by Luminex Corporation, using a panel of microspheres internally doped with two fluorescent dyes to produce up to 100 different bead identities that can be used in various applications - from HLA genotyping by oligonucleotide probe hybridization to serological profiling e.g. antibody diversity profiling, antibody identification or histocompatibility screen etc


see also