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#Planetology: reductions in the cost of pollution control; colonization of hostile planets; terraforming, which increases the maximum population of a planet; the ability to increase populations more efficiently; biological weapons and defenses against such weapons.
Queen Elizabeth II's government sends two operatives to prevent a terrorist attack on the United Kingdom using biological weapons.
A ship commanded by Captain Belinda Blowhard (Christian) called the Nemesis sets out to destroy an alien race called the Reptids, who plan to unleash a biological weapon that would reawaken all human emotion.
During a war with Afghanistan, an incurable biological weapon called the "Y-bomb", which targets only the male Y-chromosome, is used and results in the eventual deaths of 97% of the world's men.
While the question of what happened to the humans and where they went to is never fully resolved during the game, David 'Talin' Joiner, one of the game's key developers, revealed in an interview that humanity was eradicated by an airborne biological weapon (a scenario that was inspired by the Alistair MacLean novel The Satan Bug).
Tazhin met with United States Senator Richard Lugar in Astana on 7 February 2006 to discuss biological weapon nonproliferation measures and cooperation with U.S. scientists.