X-Nico

unusual facts about cancers



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AOC3

Semicarbazide-cadmium therapy has been used to alleviate the symptoms of cancers, but the APIs have significant toxicity.

DNA mismatch repair

Specifically the overwhelming majority of hereditary nonpolyposis colorectal cancers (HNPCC) are attributed to mutations in the genes encoding the MutS and MutL homologues MSH2 and MLH1 respectively, which allows them to be classified as tumour suppressor genes.

Doniach

Israel Doniach M.D., F.R.C.P. (1911–2001), pathologist and expert on the causes and diagnosis of thyroid cancers

Drinking water quality in the United States

According to GreenFacts, there is insufficient epidemiological evidence to conclude that drinking chlorinated water causes cancers.

Endometrial cancer

The antibody Herceptin, which is used to treat breast cancers that overexpress the HER2/neu protein, has been tried with some success in a phase II trial in women with uterine papillary serous carcinomas that overexpress HER2/neu.

Epithelial–mesenchymal transition

The p63 factor is involved in inhibiting EMT and reduction of certain p63 isoforms may be important in the development of epithelial cancers.

Flavones

Natural dietary flavones, found in parsley, celery, and citrus peels, reactivate DLC1 (Deleted in Liver Cancer 1) expression in breast cancer cell lines which have decreased DLC1 expression due to promoter hypermethylation, and may potentially be used as an anti-cancer agent for prevention and therapy of breast and other DLC1 downregulated cancers.

Gynecologic oncology

The Society of Gynecologic Oncology and the European Society of Gynaecological Oncology are professional organizations for gynecologic oncologists, and the Gynecologic Oncology Group is a professional organization for gynecological oncologists as well as other medical professionals who deal with gynecologic cancers.

HspE7

The candidate is being developed with a Toll-like receptor 3 (TLR3) agonist adjuvant for multiple indications, including cervical intraepithelial neoplasia (also known as cervical dysplasia or CIN), genital warts, cervical cancer, and head and neck cancers.

Jonathan D. Gray

The Grays donated $25 million to create the Basser Research Center, which focuses on cancer prevention, treatment, and research of BRCA-related, genetically-inherited cancers.

KHCC

King Hussein Cancer Center, a hospital located in Amman, Jordan specialized in treating adult and pediatric cancers.

Mir-92 microRNA precursor family

They form a classic group for the study of medullablastoma and other cancers and include mice lines that are KO for p53, Ptch1, and Ink4c.

Monroe Eliot Wall

Monroe Eliot Wall (1916 – July 6, 2002) was an American chemist, who co-discovered, with Mansukh C. Wani, paclitaxel and camptothecin, two anti-cancer drugs considered standard in the treatment to fight ovarian, breast, lung and colon cancers.

Neutron capture therapy of cancer

Finally, in August 2010 a group in Taiwan started treating patients with head and neck cancers at the Tsing Hua Open-pool Reactor (THOR) of the National Tsing Hua University.

No Evidence of Disease

No Evidence of Disease is a feature-length documentary film about N.E.D., a rock band of six gynecologic oncologists who seek to bring more attention and awareness to women's cancers.

Nventa Biopharmaceuticals Corporation

Nventa is developing HspE7 in combination with the Toll-like receptor 3 (TLR3) agonist adjuvant Poly-ICLC for multiple indications, including Cervical Intraepithelial Neoplasia (also known as cervical dysplasia or CIN), Genital Warts, Cervical Cancer, and head and neck cancers.

Olive leaf

Some recent research on the olive leaf has shown its antioxidants to be effective in treating some tumors and cancers such as liver, prostate, colon, skin and breast cancer, clinical studies lacking; Olive leaf is especially potent when used in combination with other antioxidants.

Paul Knoepfler

Knoepfler did his postdoctoral studies at the Fred Hutchinson Cancer Research Center in the laboratory of Bob Eisenman, studying Myc regulation of chromatin in stem cells and cancers of the nervous system.

Saponin

The research groups of Professor Hendrik Fuchs (Charité University, Berlin, Germany) and Dr David Flavell (Southampton General Hospital, United Kingdom) are working together toward the development of Gypsophila saponins for use in combination with immunotoxins or other targeted toxins for patients with leukaemia, lymphoma and other cancers.

Sialyl-Lewis A

Occurrence of the Sialyl Lewis A antigen, detected with the CA19-9 antibody, is highly correlated advanced epithelial cancers, such as stage III and stage IV colorectal cancers.

Splenectomy

The spleen is enlarged in a variety of conditions such as malaria, mononucleosis and most commonly in cancers of the lymphatics, such as lymphomas or leukemia.

Uterine serous carcinoma

The antibody trastuzumab (Herceptin), which is used to treat breast cancers that overexpress the HER2/neu protein, has been tried with some success in a phase II trial in women with UPSCs that overexpress HER2/neu.


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