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Common associates in the flora of the plant's basin and desert habitat include saltbush, winterfat, creosote bush, ragweed, greasewood, hopsage, and boxthorn.
These pocket mice live in soils that may be vegetated with creosote bush, palo verde, burroweed, mesquite, cholla and other cacti, and short, sparse grass, as well as in lower edges of alluvial fan with yucca, mesquite, grama, and prickle poppy.
The species form is similar to that of the common creosote bush (Larrea tridentata): small, greenish, and hemispherical with similar yellow flowers in the spring.
The classic Sonoran Desert floristic community of saguaro, palo verde, and creosote bush can be found in the southern foothills above Roosevelt Lake (650–1000 m / 2133–3281 ft), while in the range's middle elevations (1200–1800 m / 3937–5906 ft) oak scrub and juniper predominate.
Despite intensive development, the butte and its immediate surroundings continue to support a variety of native vegetation, including saguaro, Buckhorn Cholla, barrel cactus, creosote bush, palo verde, and mesquite.
Other common plants include: cholla, prickly pear, hedgehog, and barrel cactus (flowering from April to June); yucca, sotol, and agave; creosote bush and ocotillo; palo verde and mesquite trees; an amazing variety of colorful wild flowers in good years (February to March); and a lush riparian area which supports large Arizona Walnut, Arizona Sycamore, and hackberry trees.
Common ingredients of black salves include zinc chloride and chaparral, also known as creosote bush (Latin name Larrea tridentata).
One of the more notable species is the Creosote Bush (L. tridentata) of the southwestern United States and northwestern Mexico The King Clone ring in the Mojave Desert is a Creosote Bush clonal colony estimated to be 11,700 years old.
The dominant vegetation-type is commonly referred to creosote bush scrub, with palo verde, desert Ironwood, smoketree, and numerous species of cacti including cholla, saguaro, foxtail, and prickly pear.
King Clone, a Creosote bush (Larrea tridentata) in California, is believed to be the oldest living organism.