X-Nico

unusual facts about epithelial



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A549

A549 cell, a carcinomic human alveolar basal epithelial cell

Amphiregulin

This protein interacts with the Epidermal growth factor receptor to promote the growth of normal epithelial cells.

Cell adhesion molecule

Each cadherin exhibits a unique pattern of tissue distribution, such as epithelial (E-cadherins), placental (P-cadherins), neural (N-cadherins), retinal (R-cadherins), brain (B-cadherins and T-cadherins), and muscle (M-cadherins).

Epithelial–mesenchymal transition

SNAI1/Snail 1, SNAI2/Snail 2 (also known as Slug), ZEB1, ZEB2, E47 and KLF8 (Kruppel-like factor 8) can bind to E-cadherin promoter and repress its transcription, whereas factors such as Twist, Goosecoid, E2.2 (also known as TCF4), homeobox protein SIX1 and FOXC2 (fork-head box protein C2) repress E-cadherin indirectly.

The p63 factor is involved in inhibiting EMT and reduction of certain p63 isoforms may be important in the development of epithelial cancers.

Femtosecond laser intrastromal vision correction

Lower-energy femtosecond lasers may improve upon the traditional excimer laser by reducing disruption of ocular structures, with intrastromal ablation obviating the need for the damaging epithelial incision and ablation currently employed in LASIK and PRK procedures.

Fraser syndrome

The genetic background of this disease has been linked to a gene called FRAS1, which seems to be involved in skin epithelial morphogenesis during early development.

LED lamp

Tests performed at the Complutense University of Madrid indicate that prolonged exposure to the shorter blue band spectrum LED lights may permanently damage the pigment epithelial cells of the retina.

Lubiprostone

Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion.

Minimal change disease

Protein tyrosine phosphatase receptor type O - also known as glomerular epithelial protein 1 (GLEPP1) has been shown to be mutated in a number of cases.

Mixed Müllerian tumor

There is evidence that some tumors are better explained by the composition theory, due to the aggressive nature of the epithelial cells involved which tend to metastasize much more readily than the sarcomal component.

Netherton syndrome

Netherton syndrome is an autosomal recessive disorder associated with mutations in the SPINK5 gene, which encodes the serine protease inhibitor lympho-epithelial Kazal-type-related inhibitor (LEKTI).

NRG2

Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

Rhinovirus

Afterward, the virus binds to ICAM-1 (Inter-Cellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) receptors on respiratory epithelial cells.

Sialyl-Lewis A

Occurrence of the Sialyl Lewis A antigen, detected with the CA19-9 antibody, is highly correlated advanced epithelial cancers, such as stage III and stage IV colorectal cancers.

Vero cell

The Vero lineage was isolated from kidney epithelial cells extracted from an African green monkey (Chlorocebus sp.; formerly called Cercopithecus aethiops, this group of monkeys has been split into several different species).

Villus

Intestinal villus, Intestinal villus refers to any one of the small, finger-shaped outgrowths of the epithelial lining of the wall of the intestine.


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