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unusual facts about hepatocyte



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Glycogenin-1

Thanks to the presence of the glucose-6-phosphatase enzyme (G6PC), the hepatocytes are capable to turn G6PC to glucose and release it to blood so as to prevent the hypoglycemia.

Glycogenolysis

The phosphate group of glucose-6-phosphate is removed by the enzyme glucose-6-phosphatase, which is not present in myocytes, and the free glucose exits the cell via GLUT2 facilitated diffusion channels in the hepatocyte cell membrane.

Huntingtin-associated protein 1

This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate (HGS).


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