Juvenile idiopathic arthritis | juvenile idiopathic arthritis | Idiopathic infantile arterial calcification |
Recently, PTPN22 has been associated with multiple autoimmune diseases including Type I diabetes, rheumatoid arthritis, systemic lupus erythematosus, Hashimoto’s thyroiditis, Graves’ disease, Addison’s disease, Myasthenia Gravis, vitiligo, systemic sclerosis juvenile idiopathic arthritis, and psoriatic arthritis.
Brain tumor, Pseudotumor Cerebri (also known as Idiopathic Intracranial Hypertension), Cerebral venous sinus thrombosis or Intracerebral hemorrhage
M-type phospholipase A2 receptor is a major antigen in idiopathic membranous nephropathy.
In all cases, the disease is idiopathic, but is thought to involve inactivation of tumor suppressor genes (Menin gene in MEN1), or involve gain of function mutations (RET proto-oncogene MEN 2a).
Studies in 2006 showed evidence of a linkage between idiopathic scoliosis and three microsatellite polymorphisms in the MATN1 gene (encoding for Matrilin 1, cartilage matrix protein), respectively consisting of 103, 101 and 99 base pairs, .
Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonergic activity at central nervous system (CNS) and peripheral serotonin receptors.
A recent study revealed dysfunction of a particular sodium channel (Nav1.7) in a significant portion of the patient population with an idiopathic small fiber neuropathy.