X-Nico

2 unusual facts about inositol


Inositol pentakisphosphate

Inositol pentakisphosphate (abbreviated IP5) is a molecule derived from inositol tetrakisphosphate by adding a phosphate group with the help of Inositol-polyphosphate multikinase (IPMK).

Scyllo-Inositol

Researchers at the University of Toronto have found that scyllo-inositol can block the development of amyloid-beta (Aβ) plaques in the brains of transgenic mice.


Phosphatidylinositol 3-phosphate

PtdIns3P is dephosphorylated by the myotubularin family of phosphatases, on the D3 position of the inositol ring, and can be converted to PIKfyve.

Phosphatidylinositol 3,4-bisphosphate

PtdIns(3,4)P2 is dephophosphorylated by the phosphatase INPP4B on the 4 position of the inositol ring and by the TPTE (transmembrane phosphatases with tensin homology) family of phosphatases on the 3 position of the inositol ring.

Tetrahydroxy-1,4-benzoquinone

The dark purple and insoluble dipotassium salt K2C6H2O6 was prepared by Preisler and Berger in 1942, by oxidizing inositol with nitric acid and reacting the result with potassium carbonate in the presence of oxygen.


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