X-Nico

unusual facts about natural product



Candy cap

The chemical responsible for the distinct odor of the candy cap was isolated in 2012 by chemical ecologist and natural product chemist William Wood of Humboldt State University, from collections of Lactarius rubidus.

Ergotamine

Ergotamine is a secondary metabolite (natural product) and the principal alkaloid produced by the ergot fungus, Claviceps purpurea, and related fungi in the family Clavicipitaceae.

Tibbia College

Dr. Salimuzzaman Siddiqui, a notable Pakistani scientist in natural products chemistry was requested by Hakeem Ajmal Khan to initiate the Ayurvedic and Unani Tibbi Research Institute.


see also

Absinthin

The full biosynthesis of Absinthin in Artemisia absinthium has not been elucidated, but a great portion of it can be inferred from the natural product precursors required to access Absinthin.

Boromycin

It was initially isolated from the Streptomyces strain Streptomyces antibioticus, and is notable for being the first natural product found to contain the element boron.

Chaitan Khosla

His early research on natural product polyketides led to the founding of Kosan Biosciences in 1995.

Chelerythrine

It is also the major active natural product found in the plant Zanthoxylum clava-herculis, exhibiting anti-bacterial activity against Staphylococcus aureus.

Discovery and development of statins

In 1978, Alfred Alberts and colleagues at Merck Research Laboratories discovered a new natural product in a fermentation broth af Aspergillus terreus, their product showed good HMGR inhibition and they named the product mevinolin, which later became known as lovastatin.

IPI-926

The process begins with cyclopamine extracted from harvested Veratrum californicum which is taken through a series of alterations resulting in an analogue of the natural product cyclopamine, making IPI-926 the only compound in development/testing that is not fully synthetic.

Rubicordifolin

Rubicordifolin is a natural product that is produced by Rubia cordifolia, a plant that is a member of the Rubiaceae family.

Topotecan

Camptothecin is a natural product extracted from the bark of the tree Camptotheca acuminata.