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He played Christian Aumont on the TV series Sleeper Cell, where he met his fiancée, actress Melissa Sagemiller.
From 2005 to 2010, Walker played many guest roles on TV shows, such as Sleeper Cell, ER, Boston Legal, Law & Order, CSI: Crime Scene Investigation, Southland and Law and Order: SVU.
In December 2002, the television program America's Most Wanted featured Amer, stating that he was an airline pilot who may have "snuck back into the U.S" to work with al-Qaeda sleeper cells.
Diego served as music sound designer for TV shows The Tudors, Moonlight and Sleeper Cell.
His notable television roles include Taylor Newton in four seasons of the CBS sitcom Evening Shade, Dr. Todd Hooper on Judging Amy, Rich Connelly in the 2005 NBC television series Surface, Agent Warren Russell on the Showtime series Sleeper Cell and most recently Stan Rizzo on the AMC series Mad Men.
Alex Nesic became engaged in July 2006 to his Sleeper Cell co-star Melissa Sagemiller after he proposed to her in the South of France.
His 2006 album Treasure Island was a change of direction, seeing both a concerted shift to more overtly political themes (songs such as Knuckledraggers, Sleeper Cell and Intelligent Design - spliced together from audio clips of George W. Bush's speeches on the war on terror - were all highly critical of the Bush regime) and to more historical perspectives.