X-Nico

unusual facts about transcription factor



Atrioventricular septal defect

TBX2 is a T-box transcription factor and is usually expressed during various areas of embryogenesis.

Doublesex

All of these are transcription factors with a zinc finger DNA-binding domain (known as the DM domain) and are involved in sex-specific differentiation.

FOSB

These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.

Pre-locus coeruleus

Subsequently, it was discovered that every c-Fos-positive neuron in the pre-LC (after sodium deprivation) also expresses the transcription factor FOXP2.

Primitive streak

Activation of various secreted factors (Vg1, Nodal, Wnt8C, FGF8 and Chordin) and transcription factors (Brachyury and Goosecoid) adjacent to the site of streak formation is required for this process.


see also

ANA773

TRAF6 activates NF-κB transcription factor ‘Mitogen Activated Protein Kinases’ (MAPK) and ‘c-jun NH2 Terminal Kinases' (Jnk) which activates the transcription factor ‘Activating Transcription Factor 2’ (ATF2).

Aux

Auxin, a class of plant hormones and morphogens, or associated molecules such as auxin influx transporters (e.g. AUX1) and the Aux/IAA early auxin responsive transcription factor family (e.g. AUX22).

Focal facial dermal dysplasia

Type II appears to be due to mutations in the transcription factor TWIST2 on chromosome 2.

Hypotrichosis–lymphedema–telangiectasia syndrome

It is associated with a rare mutation of the transcription factor gene SOX18.

IPEX syndrome

IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) is a rare disease linked to the dysfunction of the transcription factor FOXP3, widely considered to be the master regulator of the regulatory T cell lineage.

Mitochondrial biogenesis

The NRFs, in turn, activate the mitochondrial transcription factor A (tfam), which is directly responsible for transcribing nuclear-encoded mitochondrial proteins.

National Transportation Research Center

For the sigma N-transcription factor activator protein in prokaryotes, see NtrC

Nuocyte

Nuocytes have been shown to have a lymphoid origin and a developmental pathway that is dependent upon the transcription factor RORα and Notch signalling.

Oscillating gene

Clock- Clock, also known as Circadian Locomotor Output Cycles Kaput, is a transcription factor in the circadian pacemaker of mammals.

RE1-silencing transcription factor

RE1-silencing transcription factor has been shown to interact with RCOR1.

Saethre–Chotzen syndrome

Linkage analysis and chromosomal rearrangement revealed the cause of SCS to be mutations in the TWIST gene (twist transcription factor gene) located on chromosome 7p21.

Soulless

Soulless (biology), a historic name for PHOX2A, a human transcription factor

Stauprimide

Stauprimide interacts with NME2 (PUF) transcription factor to down-regulate c-Myc expression, leading to differentiation of stem cells.

Ulla Hansen

She has concentrated on the LSF transcription factor, which is involved in oncogenesis.