Nothing is known of his childhood and his name cannot be found in the records of the Academia Julia.
The University of Helmstedt, official Latin name: Academia Julia ("Julius University"), was a university in Helmstedt in the Duchy of Brunswick-Wolfenbüttel that existed from 1576 until 1810.
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Following studies at the Collegium Carolinum in Braunschweig, he continued his education at the University of Helmstedt, where one of his instructors was chemist Lorenz von Crell (1744-1816).
1805 from the University of Helmstedt under Justus Ferdinand Christian Loder and Gottfried Christoph Beireis.
His friends, however, stood by him, and he retained the position he held in the Lutheran Church, teaching theology at the University of Helmstedt until his death.
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On his return in 1614, he was appointed professor of theology at Helmstedt by the duke of Brunswick, who had admired the ability he displayed when a young man in a dispute with the Jesuit Augustine Turrianus.
A particular form of Renaissance architecture in Germany is the Weser Renaissance, with prominent examples such as the City Hall of Bremen and the Juleum in Helmstedt.
He studied oriental languages at the universities of Jena and Leipzig, and in 1690 he was called to the chair of oriental languages at Helmstedt.
He studied medicine at Helmstedt, Groningen and Leyden and afterwards traveled to Italy, France and England for scientific studies.
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He received his doctorate in 1663 in Angers (France) and in 1664 accepted a professorship in medicine at the University of Helmstedt.
At the age of fourteen, he entered the University of Helmstedt where, after nearly a decade of taking courses offered by the philosophical and medical faculties, he took his M.D. in 1768.
In 1711 he was appointed professor of anatomy and surgery at the University of Altdorf, and from 1720, was a professor of anatomy and surgery at Helmstädt, where he remained for rest of his life.
Also in that year, he was given a position at the Akademie der Naturforscher, and soon afterwards became lecturer in Rhetoric, Antiquities, and Poetry at the University of Helmstedt.
He studied medicine at the University of Helmstedt under Lorenz Heister (1683–1758) and Brandanus Meibom (1678–1740), who was the son of Heinrich Meibom (1638–1700).
In 1761 he was appointed pastor, professor of theology and general superintendent in the University of Helmstedt.
Arama's works were likewise esteemed by the Christian world; for in 1729 an academical dissertation by M. A. J. van der Hardt, of the University of Helmstedt, was published under the title Dissertatio Rabbinica de Usu Linguæ in Akedat Ischak, treating of section 62 of Arama's work, giving it in Hebrew with Latin translation.