As a class, they represent a significant source of the world's Cu, Zn, Pb, Au, and Ag ores, with Co, Sn, Ba, S, Se, Mn, Cd, In, Bi, Te, Ga and Ge as co- or by-products.
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Further, the municipality of Castro Verde is crossed by the Iberian Pyrite Belt, composed of a massive volcanogenic sulfide deposit (VMS) associated with the polymetallic flanks of volcanic cones in the form of pyrite, chalcopyrite, sphalerite, galena and cassiterite, that begins in Aljustrel, spreads through the lower Alentejo and extends into southern Spain.
In central Manitoba lies the Flin Flon greenstone belt, which is one of the largest Paleoproterozoic volcanic-hosted massive sulphide districts in the world, containing 27 copper-zinc-(gold) deposits from which more than 183 million tonnes of sulphide have been mined.