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2 unusual facts about Aicardi–Goutières syndrome


Aicardi–Goutières syndrome

Aicardi–Goutières syndrome (AGS) is a congenital immune-mediated neurodevelopmental disorder caused by mutations in the SAMHD1, TREX1, or Ribonuclease H2 (RNASEH2A, RNASEH2B, RNASEH2C) genes.

In 1984, Jean Aicardi and Francoise Goutieres described eight children from five families presenting with severe early onset encephalopathy.


Giorgio Matteo Aicardi

In 1986 a posthumous exhibition of Aicardi's paintings was held in his native Finalborgo at the "Chiostri di Santa Caterina" sponsored by C.R.S. (Cassa di Risparmio di Savona), Carige Bank.

In 1906 Aicardi, aged 15, painted his first "fresco" of Santa Teresa (his sister Ernesta was his model), which still can be seen in the dome of "San Biagio Basilica" in his native Finalborgo (Savona).

Giorgio Matteo Aicardi was born on 18 September 1891 in Finalborgo (Province of Savona), Italy, the eighth of Giuseppe Aicardi and Francesca Muzio's nine children.


see also