When the glucose concentration outside the cell is high, glucose molecules move into the cell by facilitated diffusion, down its concentration gradient through the GLUT2 transporter.
Cell nucleus | Soft Cell | Cell biology | Cell | Beta | Tau Beta Pi | cell | cell (biology) | B-cell activating factor | Phi Beta Sigma | Cell (journal) | Cell (biology) | beta | T cell | cell membrane | Zeta Beta Tau | TGF beta 1 | Mesenchymal stem cell | Cell membrane | Beta Gamma Sigma | The Beta Band | Tau Beta Sigma | Phi Beta Kappa Society | Hematopoietic stem cell transplantation | cell culture | Cell Biology | Beta Israel | The Plant Cell | TGF beta receptor 2 | Solar cell |
Some of these pathways include Rap, Erk1/2, MAPK, B-RAF, PI3-K, cAMP, PKA, and TORC2 that are activated to initiate exocytosis, proinsulin gene expression and translation, increase insulin biosynthesis, and genetically increase beta cell proliferation and neogenesis.
Islet amyloid polypeptide or Amylin, a protein produced by the pancreatic beta-cell that has been linked to type II Diabetes.
:KATP is also the ATP-sensitive potassium channel responsible for pancreatic beta-cell insulin release.