X-Nico

2 unusual facts about Cartilage–hair hypoplasia


Cartilage–hair hypoplasia

An association between mutations near or within the ncRNA component of RNase MRP, RMRP, has been identified.

Celebrity Big Brother 6

Troyer is most notable for his height 2 ft 8 in (0.81 m), as a result of cartilage–hair hypoplasia dwarfism.


Alf Ward

He joined the "Saints" 1908 summer tour of Europe; at Leipzig, in the final match of the tour, Ward displaced the cartilage of his right knee.

Cartilage

Conversely, chondrostatin, an ingredient of cartilage, is being investigated by Washington University researchers for its potential ability to shrink breast and musculoskeletal tumors.

Jack Maddock

Unable to continue working in his former role as a carpenter in his father's factory, let alone play professional football he spent 75 guineas of his money to pay for surgery to remove his damaged cartilage; the operation was a success.

Joe Mercer

The Everton manager Theo Kelly accused Mercer of not trying in an international against Scotland, but in reality Mercer had sustained a severe cartilage injury.

John Charnley

Charnley's research was based on two different aspects: clinical, for the treatment of patients with osteoarthritis, and biomechanical, with experiments to determine the fundamentals of bony union and the conditions governing the spontaneous regeneration of articular cartilage.

Kitten's Joy

He was retired after the Million due to damaged cartilage in his left knee and now stands at Ramsey Farm in Nicholasville, Kentucky.

Labrum

Acetabular labrum, a ring of cartilage that surrounds the acetabulum, the socket of the hip joint

Glenoid labrum, a lip-like projection of cartilage on the human scapula surrounding the joint between the humerus and the shoulder blade

Meckel's cartilage

Johann Friedrich Meckel, the Younger discovered this cartilage in 1820.

Non-coding RNA

Mutations within RNase MRP have been shown to cause cartilage-hair hypoplasia, a disease associated with an array of symptoms such as short stature, sparse hair, skeletal abnormalities and a suppressed immune system that is frequent among Amish and Finnish.

Scoliosis

Studies in 2006 showed evidence of a linkage between idiopathic scoliosis and three microsatellite polymorphisms in the MATN1 gene (encoding for Matrilin 1, cartilage matrix protein), respectively consisting of 103, 101 and 99 base pairs, .


see also