X-Nico

3 unusual facts about Non-coding RNA


Non-coding RNA

Mutations within RNase MRP have been shown to cause cartilage-hair hypoplasia, a disease associated with an array of symptoms such as short stature, sparse hair, skeletal abnormalities and a suppressed immune system that is frequent among Amish and Finnish.

For example, a riboswitch can directly bind a small target molecule, the binding of the target affects the gene's activity.

Xist (X-inactive-specific transcript) is a long ncRNA gene on the X chromosome of the placental mammals that acts as major effector of the X chromosome inactivation process forming Barr bodies.


1000 Plant Genomes Project

Since only the transcriptome is being sequenced, the project will not reveal information about gene regulatory sequence, non-coding RNAs, DNA repetitive elements, or other genomic features that are not part of the coding sequence.

Benoit Coulombe

Benoit Coulombe is a Canadian scientist whose research focuses on the mechanisms by which regulated protein–protein, protein–DNA and protein–RNA interactions control the activity of RNA polymerase II, the molecular machine that synthesizes all messenger RNA (mRNA) and some small-nuclear RNA (snRNA) in eukaryotes.

Mir-395 microRNA precursor family

mir-395 is a non-coding RNA called a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified.

NrrF RNA

NrrF is a non-coding RNA which is regulated by the Ferric uptake regulator (Fur) protein in bacteria.

Vibrio regulatory RNA of OmpA

VrrA (Vibrio regulatory RNA of OmpA) is a non-coding RNA that is conserved across all Vibrio species of bacteria and acts as a repressor for the synthesis of the outer membrane protein OmpA.


see also

PRNA

NoRC associated RNA, a non-coding RNA element which regulates ribosomal RNA transcription

R43

Small nucleolar RNA R43, a plant non-coding RNA molecule which functions in the modification of other small nuclear RNAs

Z12

Z12 small nucleolar RNA, a non-coding RNA molecule which functions in the modification of other small nuclear RNAs