Whereas in its infancy, it focused primarily on country music, the show has branched out considerably and has featured several high profile celebrity guests, such as Jenny McCarthy, Bill Engvall, UFC fighters Chuck Liddell, Forrest Griffin, and Matt Hughes, Piers Morgan, Larry the Cable Guy, Chelsea Handler, Jorge Cruz, and many more.
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At his annual state of the industry address at Montreal's "Just For Laughs" festival, he criticized Dane Cook, Louis CK, Chelsea Handler and Jay Leno.
His on-air interaction with off-camera staff and sidekicks is somewhat in the vein of what Howard Stern and Chelsea Handler would later do.
The book was followed by a "Lies That Chelsea Handler Told Me" Tour, on which Handler was accompanied by the Comedians of Chelsea Lately.
He has even performed with comedians from Chelsea Handler's hit late-night talk show on E!, Chelsea Lately.