X-Nico

6 unusual facts about Chemical synthesis


Atomism

:Chemical analysis and synthesis go no farther than to the separation of particles one from another, and to their reunion.

Choh Hao Li

In 1970 he succeeded in synthesizing this hormone, the largest protein molecule synthesized up to that time.

Dioscorea bulbifera

These varieties contain the steroid, diosgenin, which is a principal material used in the manufacture of a number of synthetic steroidal hormones, such as those used in hormonal contraception.

Medwell Capital

Medwell Capital obtained an exclusive worldwide license to proprietary technology developed at the MS Patient Care and Research Clinic at the University of Alberta for the treatment of MS. The compound, dirucotide (MBP8298), is a synthetic myelin basic protein peptide composed of 17 amino acids which is intravenously injected (every six months) into MS patients as a therapeutic treatment.

Rodney H. Banks

In 1980, he received his Ph.D. in inorganic/physical chemistry from the University of California, Berkeley, where he worked for Nobel laureate and fellow Perkin medal winner Glenn Seaborg on the synthesis and characterization of volatile actinide compounds.

Zirconium tungstate

This phase is thermodynamically unstable at room temperature with respect to the binary oxides synthesised by heating stoichiometric quantities of these oxides together and then quenching the material by rapidly cooling it from approximately 900 °C to room temperature.


Dextroamphetamine

Racemic amphetamine was first synthesized under the chemical name "phenylisopropylamine" in Berlin, 1887 by the Romanian chemist Lazar Edeleanu.

DNA demethylation

The passive process takes place in the absence of methylation of newly synthesised DNA strands by DNMT1 during several replication rounds (for example, upon 5-Azacytidine treatment).

Ethinyl estradiol

The first orally active semisynthetic steroidal estrogen, EE (17α-ethynylestradiol), the 17α-ethynyl analog of E2, was synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering AG in Berlin.

Ethisterone

The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone or 19–norandrostane), the 17α-ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone.


see also

Clayton Heathcock

Heathcock is known for tackling the chemical synthesis of complex, polycyclic natural products, often possessing unusual biological activity including Daphniphyllum alkaloids, altohyrtin, zaragozic acid, spongistatins, and many others.

Grand Challenges In Global Health

At Virginia Tech University, Dr. Jeffery Bloomquist and a team are using molecular modeling and a new chemical synthesis method known as “click chemistry” to produce insecticides targeted to the primary malaria vector mosquitoes, Anopheles gambiae.