Research suggested that most of the adverse effects of NSAIDs were mediated by blocking the COX1 (constitutive) enzyme, with the analgesic effects being mediated by the COX2 (inducible) enzyme.
enzyme | Enzyme inhibition | enzyme inhibition | Restriction enzyme | Enzyme inhibitor | enzyme inhibitor | Enzyme Commission number | Enzyme | Constitutive enzyme | Adaptive enzyme | Phospholipase cleavage sites. Note that an enzyme that displays both PLA1 and PLA2 activities is called a ''Phospholipase B | Enzyme Records | Enzyme activator | COP9 constitutive photomorphogenic homolog subunit 5 |