The Fred Mertz character, the actor who portrayed him (William Frawley), and some of their costumes are memorialized in the Lucille Ball-Desi Arnaz Center in Jamestown, New York (Lucille Ball's real-life hometown).
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It had been mentioned that he was once a Golden Gloves boxer, and Fred wears a sweater from Golden Gloves 1909 in episode #76.
Referenced in Season 5: The Fox Hunt of "I Love Lucy" when Fred Mertz notes, "Yeah, she didn't exactly look like Johnny Longden sitting up there."
Fred Astaire | Fred Frith | Fred Quimby | Fred Thompson | Fred Beckey | Fred MacMurray | Fred Willard | Fred Hersch | Fred | Fred Seibert | Fred R. Harris | Fred Olen Ray | Fred Neil | Fred Hoyle | Fred Flintstone | Fred Couples | Fred Noonan | Fred Wilson | Fred Upton | Fred Rogers | Fred Gwynne | Fred Williamson | Fred Van Lente | Fred Trueman | Fred Titmus | Fred Silverman | Fred Schneider | Fred Schepisi | Fred M. Vinson | Fred Lynn |
Ethel and Fred Mertz (Vivian Vance, William Frawley) arrive and drop off favors for Little Ricky's fifth birthday party, which is scheduled for Saturday.
William Frawley later portrayed "Fred Mertz" in the television series I Love Lucy.