The receptor activates insulin gene expression by activation of MAPK through a mechanism dependent on MEK but independent of both Raf and Ras3.
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GSK716155 (Albugon) is a recombinant human glucagon-like peptide (GLP)-1-Albumin protein created using Human Genome Sciences' proprietary albumin fusion technology, which involves fusing the gene that expresses human albumin to the gene that expresses a therapeutically active protein (GLP-1)1.