An entire skull, found in the Lower Pliocene beds of Eppelsheim, Hesse-Darmstadt in 1836, measured 4 ft (1.2 m) in length and 3 ft (.9 meters) in breadth, indicating an animal exceeding modern elephants in size.
Wilhelm Leichum (May 12, 1911, Neu-Isenburg, Grand Duchy of Hesse – July 19, 1941, Gorky) was a German athlete who competed mainly in the long jump and 100 metres.
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Abraham Samuel Bacharach was a Rabbi, born about 1575; died in Gernsheim, Grand Duchy of Hesse, May 26, 1615.
Prince Alexander (1823–1888) was the third son of Grand Duke Louis II of Hesse and by Rhine and of Wilhelmina of Baden yet it was openly rumoured his biological father was actually Baron Augustus de Senarclens, his mother's chamberlain.
Born in Schlitz, Hesse-Darmstadt, Germany, he studied in Europe before coming to the United States, where he taught at a number of different locations.
The type specimens for Chalicotherium goldfussi were found in the Upper Miocene strata of the Dinotherien-sande beds near Eppelsheim, in the Grand Duchy of Hesse, Germany.
He was born March 3, 1827 in Rimbach, Hesse-Darmstadt, Germany, the son of Wilhelm and Mary (Albrecht) Gutmann.
The Hessian Ludwig Railway (Hessische Ludwigs-Eisenbahn-Gesellschaft, HLB), which was established in the Grand Duchy of Hesse recognized the importance of the HLB for the expansion of railway services in the Rhine-Main region, particularly to the province of Upper Hesse (an exclave of the Grand Duchy), from the Rhine-Main area to Bavaria and via the Kinzig valley to Bebra.
Franz Völker (March 31, 1899, Neu-Isenburg, Grand Duchy of Hesse - December 4, 1965, Darmstadt, Hesse) was a dramatic tenor who enjoyed a major European career.
Born in Weiterstadt-Gräfenhausen, Grand Duchy of Hesse, he described a number of plant species in his published works, taking a particular interest in legumes and malvaceae.
Born in Goddelau (now part of Riedstadt) in the Grand Duchy of Hesse as the son of a physician, Büchner attended a humanistic secondary school that focused on modern languages (including French, Italian and English).
Heinrich XIX was born at Offenbach, Grand Duchy of Hesse, elder surviving son of Heinrich XIII, Prince Reuss of Greiz (1747–1817), (son of Heinrich XI, Prince Reuss of Greiz and Countess Conradine Reuss of Köstritz) and his wife, Princess Wilhelmine Louise of Nassau-Weilburg (1765–1837), (daughter of Charles Christian, Prince of Nassau-Weilburg and Princess Carolina of Orange-Nassau).
Heinrich XIX was born at Offenbach, Grand Duchy of Hesse, younger surviving son of Heinrich XIII, Prince Reuss of Greiz (1747–1817), (son of Heinrich XI, Prince Reuss of Greiz and Countess Conradine Reuss of Köstritz) and his wife, Princess Wilhelmine Louise of Nassau-Weilburg (1765–1837), (daughter of Charles Christian, Prince of Nassau-Weilburg and Princess Carolina of Orange-Nassau).
In 1831 he became counselor of the treasury in the Ministry of the Interior of Hesse-Darmstadt, and in 1836 counselor of the cabinet, in which capacity he officiated as commissioner of the Hessian government in the Landtag.
Pierre Jean Édouard Desor (13 February 1811, Friedrichsdorf, Grand Duchy of Hesse – 23 February 1882) was a German-Swiss geologist and naturalist.
Major Theodor Weissenberger (born 21 December 1914 in Mühlheim am Main, Grand Duchy of Hesse, killed in a car racing accident 10 June 1950 on the Nürburgring) was a German World War II fighter ace who served in the Luftwaffe from 1936 until the end of World War II in 1945.
Born Karl Emil Bender at König im Odenwald in the Grand Duchy of Hesse-Darmstadt, he was the eldest of six children.
Bad Nauheim was a Kurhessen enclave within the Grand Duchy of Hesse exclave of Oberhessen through which the line ran to Gießen.