In 1908, American surgeon Leo Buerger (1879–1943) further described the disease, and in 1924 published a monograph based on analyses taken from 500 patients.
Initially Buerger practiced at the Lenox Hill Hospital (1901-1904), then the Mount Sinai Hospital (1904–05), then as a volunteer in the surgical clinic at Wrocław with study visits to Vienna and Paris.
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