He reevaluates August Weismann's model of the cell compartmentalization of somatic and germline cell lineages (see Weismann barrier), and argues that the vision of the individual taken by the modern synthesis is insufficient to explain the early evolution of development or ontogeny.
Leo Buss in his book The Evolution of Individuality proposes that much of the evolution of development in metazoans reflects the conflict between selective pressures acting at the level of the cell and those acting at the level of the multicellular individual.
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