The southern terminus of the southern segment of Nebraska Highway 57 is northeast of Leigh at Nebraska Highway 91, while its northern terminus is at U.S. Highway 275 north of Stanton.
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It goes north into farmland, through Carroll, and meets U.S. Highway 20 east of Belden.
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The southern terminus of the northern segment of Highway 57 is south of Carroll at Nebraska Highway 98, while its northern terminus is north of Hartington at an intersection with Nebraska Highway 12.
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