This work was under the direction of architects John McAslan + Partners and involved a team of specialist contractors for expert restoration, or replication of, the original features of the Mackintosh period scheme.
He became director of the Carnegie Institution in 1962 and was awarded the Nobel Prize in Physiology or Medicine in 1969, shared with Salvador Luria and Max Delbrück for their discovery on the replication of viruses and their genetic structure.
Additionally, Dbf4 stimulates Cell division cycle 7-related protein kinase (Cdc7) activity, which promotes activation of replication origins.
In molecular biology, the Avian encephalitis virus cis-acting replication element (CRE) is an s an RNA element which is found in the coding region of the RNA-dependent RNA polymerase in Avian encephalitis virus (AEV).
He developed a biochemical system to study DNA replication-coupled chromatin assembly in a test tube and discovered proteins such as Chromatin Assembly Factor-1 (CAF-1) that cooperate with the DNA replication machinery to assemble new histones onto the DNA.
As replication requires the use of RNA intermediate, viruses from the Caulimoviridae family are not true dsDNA viruses - instead they are termed DNA reverse-transcribing viruses.
The basic assumption of the model is that life should fundamentally and essentially have three properties: metabolism, self-replication, and a bilipid membrane.
This instability is usually due to the propensity of these regions to misalign during DNA repair, exacerbated by defects of the appearance of replication proteins (like FEN1 or Pol δ) that ubiquitously affect the integrity of the genome.
The 286 kDa protein is a polyprotein involved in virus replication and has four conserved domains: methyltransferase, protease, helicase and an RNA dependent RNA polymerase.
In his short story "Crabs on the Island" (1958) Anatoli Dneprov speculated on the idea that since the replication process is never 100% accurate, leading to slight differences in the descendants, over several generations of replication the machines would be subjected to evolution similar to that of living organisms.
The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co-protease activity of RecA.
The passive process takes place in the absence of methylation of newly synthesised DNA strands by DNMT1 during several replication rounds (for example, upon 5-Azacytidine treatment).
DnaA is a replication initiation factor which promotes the unwinding or denaturation of DNA at oriC, during DNA replication in prokaryotes.
E2F target genes encode proteins involved in DNA replication (for example DNA polymerase, thymidine kinase, dihydrofolate reductase and cdc6), and chromosomal replication (replication origin-binding protein HsOrc1 and MCM5).
The first full electronic church organ was built in 1939 by Jerome Markowitz, founder of the Allen Organ Company, who had worked for years to perfect the replication of pipe organ sound through the use of radio tube based oscillator circuitry.
Errett Callahan (born 1937), American archaeologist, flintknapper, and pioneer in experimental archaeology and lithic replication studies
In this way a great deal has been learned in recent years about the mechanochemical coupling in the enzymes responsible for muscle contraction, transport in the cell, energy generation (F1-ATPase), DNA replication and transcription (polymerases), DNA unknotting and unwinding (topoisomerases and helicases), and so on.
She studied Environmental Art at the Glasgow School of Art and had a residency in Cromarty, where she recorded people imitating the sea on the CD 100 Breaths, 100 Waves, and a replication of a dawn chorus on Salutations To The Sun.
The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B.
In addition to having septate basidia, heterobasidiomycetes also frequently possess large irregularly shaped sterigmata and spores that are capable of self-replication - a process where a spore, instead of germinating into a vegetative hypha, gives rise to a sterigma and a new spore, which is then discharged as if from a normal basidium.
Homer Jacobson illustrated basic self-replication in the 1950s with a model train set – a seed "organism" consisting of a "head" and "tail" boxcar could use the simple rules of the system to consistently create new "organisms" identical to itself, so long as there was a random pool of new boxcars to draw from.
Reverse transcription of the genome occurs at a later step in the replication cycle, which results in the infectious particles having DNA rather than RNA, this also leads to less integration in the host genome.
iOra Geo-Replicator is a geo-replication technology which improves Microsoft SharePoint access for users at the edge of large military, commercial and aid organizations.
The database classifies viruses based primarily on their chemical characteristics, genomic type, nucleic acid replication, diseases, vectors, and geographical distribution, among other characteristics.
While returning to Montreal for his Daughter’s admission to McGill University in 1999, Galat was asked by John Gilman, founder and former Chief Executive Officer of FieldTurf, to help introduce the upstart company called FieldTurf, a replication of a grass sports field.
Bramhall's A Just Vindication of the Church of England from the Unjust Aspersion of Criminal Schism (1654) was answered by the titular Bishop of Chalcedon, and Bramhall replied to this with Replication in 1656, where he prays that he might live to see the day when all Christian churches united again.
Helicases separate double strands of nucleic acids prior to transcription or replication.
Multi-master replication, a method of replication employed by databases to transfer data or changes to data across multiple computers
Dr Kary Mullis, who won a Nobel Prize for his work on DNA replication, advised the defence throughout the trial, but was not called to testify.
In the spirit of Julien Offray de La Mettrie (1709–1751) he derives understanding of humanity, including culture and religion, not from the evolutionary approach — which he does not oppose, but transcends — but from considering humans as self reproducing, intelligent bio-mechanical robots, or biobots.
In molecular biology, the Norovirus cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase in Norovirus.
The same basic plan was intended for replication in towns throughout the colony; however, Darien, Georgia is the only other living town in which the original design has survived.
The use of an open source virtual learning environment, along with the ability for people to download and upload materials in various formats (from an RSS to a print to an IMS Common Cartridge) encourages replication of the content and enables interoperability with other provider’s content management systems.
For instance, etoposide binds and stabilizes the temporary break caused by the enzyme, disrupts the reparation of the break through which the double-stranded DNA passes, and consequently stops DNA unwinding and replication.
Because the binding of the polymerase to the template is the rate-limiting step in DNA synthesis, the overall rate of DNA replication during S phase of the cell cycle is dependent on the processivity of the DNA polymerases performing the replication.
CopA-like RNA, an antisense RNA involved in replication control of the plasmid.
RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses.
PFF1 consists of an origin of replication, oriV, an origin of transfer, oriT, a gene coding for plasmid replication proteins, trfA, and two antibiotic resistance genes, bla and cat, which confer resistance to Ampicillin and Chloramphenicol, respectively.
Activation of the SOS genes occurs after DNA damage by the accumulation of single stranded (ssDNA) regions generated at replication forks, where DNA polymerase is blocked.
Even then, certain conditions must be met such as chromosome integrity, the state of chromosomal replication, and the functioning of the Krebs cycle.
Contrary to the non-commercial RepRap project founded By Adrian Bowyer, Ultimaker is not focused on an end-goal of self-replication.
Unlike traditional anti-HIV medications that seek solely to reduce viral replication, AV-HALTs also target the chronic immune system hyperactivation now known to contribute to the loss of CD4 T helper cells and disease progression to AIDS.
Vpx enhances HIV-2 replication in humans by counteracting the host factor SAMHD1.