Sonic hedgehog, an important protein during vertebrate organogenesis
Sonic hedgehog, a biological term referring to one of three proteins in the mammalian signaling pathway family called hedgehog
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Mouse mutants: Rab23 is an essential negative regulator of the mouse Sonic hedgehog signaling pathway.
For instance, different levels of sonic hedgehog and NODAL proteins on opposite sides of the embryo have been linked to proper bending of the embryonic heart, responsible giving it its asymmetrical form.
Stimulation of the patched receptor by the sonic hedgehog ligand leads to translocation of SMO to the primary cilium.