In 1824 she gave an acclaimed portrayal of Isaura in Giacomo Meyerbeer's Margherita d'Anjou at the Teatro Comunale di Bologna.
The premiere performance took place on 31 October 2000, at the Teatro Comunale di Bologna.
Some of the performances in which Machaidze has taken part have also been videotaped and released on DVD, including: Il Trittico, La Scala, 2008; Romeo et Juliette, Salzburger Festspiele 2008; I Puritani, Teatro Comunale di Bologna or recently La Bohème with Anna Netrebko in Salzburg.
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Mascagni: Le Maschere (Maria Josè Gallego, Vincenzo La Scola, Amelia Felle, Giuseppe Sabbatini, et al.; Orchestra and Chorus of the Teatro Comunale di Bologna).
In 1836 Sacchi was committed to the Teatro Comunale di Bologna where she portrayed Eudora in Donizetti's Belisario and Imelda in Donizetti's Parisina among other roles.