X-Nico

2 unusual facts about WHEP-TRS protein domain


WHEP-TRS protein domain

They are found in variable numbers in a particularly common protein, named, glutamyl-prolyl tRNA synthetase(EPRS).

EPRS is a component of the interferon-gamma-activated inhibitor of translation (GAIT) complex, which interacts with stem-loop elements (GAIT elements) in mRNAs encoding proinflammatory proteins, for example, vascular endothelial growth factor-A (VEGFA).


WHEP

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see also